Bullous systemic lupus erythematosus (BSLE) is a rare cutaneous . Lúpus eritematoso sistêmico bolhoso – diagnóstico diferencial com dermatite herpetiforme. O lúpus eritematoso sistêmico pode apresentar inúmeras lesões cutâneas. As lesões bolhosas específi cas do lúpus, apesar de raras, apresentam. Systemic lupus erythematosus (SLE) can cause numerous skin lesions. Despite being rare, Lúpus eritematoso sistêmico bolhoso em gestante: relato de caso.

Author: Shaktizilkree Tygoshicage
Country: Somalia
Language: English (Spanish)
Genre: Health and Food
Published (Last): 26 August 2015
Pages: 256
PDF File Size: 9.72 Mb
ePub File Size: 16.50 Mb
ISBN: 591-5-80152-210-1
Downloads: 53630
Price: Free* [*Free Regsitration Required]
Uploader: Banos

Approved by the Advisory Board and accepted for publication on National Center for Biotechnology InformationU. They preferentially affect the torso and supraclavicular region but may also affect the mucosae, particularly in the mouth and lupuz. J Am Acad Dermatol. Chronic cutaneous discoid lupus erythematosus CCDLE or discoid lupus eryhthematosus DLE is a rare chronic auto-immune bophoso and the most common clinical variant of the lupus erythematosus LE.

Guilherme Canho Bittner 1 Dr. The patient was then started on hydroxycloroquine mg daily with clinical improvement in 45 days Figure 4.

Patients should therefore be tested for this deficiency before being treated with this drug. Discoid lupus erythematosus presenting with cysts, comedones, and cicatricial alopecia on the scalp. Adjuvant therapies must also be used in cases that do not respond to or are intolerant of dapsone; the use of azathioprine, antimalarial agents, mycophenolate mofetil and cyclophosphamide has lupis reported in the literature.

TOP Related Posts  GOMORRA KSIKA PDF

Rio Branco, 39 Ultraviolet radiation, high anti-Ro antibody titers, deposition of immune complexes and abnormal cellular immunity are considered to be responsible for damage to the basal layer. Bullous systemic lupus erythematosus: Anti-type VII collagen antibodies are not formed.

During twelve months of follow-up no signs or symptoms of systemic disease were observed. Received May 22; Accepted Sep The diagnosis of comedonic DLE was confirmed mainly by the histopathological changes.

Comedonic lupus: a rare presentation of discoid lupus erythematosus

Al-Refu K, Goodfield M. It is an acquired bullous disease caused by anti-type VII collagen antibodies. The dermatologic examination showed lightly-colored violaceous, infiltrated plaques of various sizes and atrophic scars on the right ear, dorsal aspect of the nose and chin.

Childhood-onset bullous systemic lupus erythematosus. Other less frequent side effects include neuropathy and bone marrow depression.

Lúpus eritematoso sistêmico bolhoso: diagnóstico diferencial com dermatite herpetiforme

Bullous systemic lupus erythematosus: Bullous systemic lupus erythematosus. Direct immunofluorescence lupsu a linear or granular deposition of IgG, IgA and C3 in the basement membrane zone. How to cite this article. SLE with blisters is characterized by polycyclic lesions with blisters on the edges. Pruritus may or may not be present.

We present a typical case of bullous systemic lupus erythematosus and emphasize the importance of clinical and histopathological differential diagnosis with dermatitis herpetiformis. Luiz Carlos Bolhosoo 1 Dr. Blisters are formed as a result of severe damage to the basal layer and consequent separation of the basement membrane from keratinocytes.

TOP Related Posts  CATALOGO DI MESSIER PDF

Patients with glucosephosphate dehydrogenase deficiency may present with severe hemolysis when taking dapsone.

Support Center Support Center. Please review our privacy policy. Int Soc Dermatol ; There was improvement of the pruritus and the number of comedones Figure 3.

There was a problem providing the content you requested

Clinical and laboratory abnormalities in this patient confirmed the suspicion of BSLE. Nelise Ritter Hans-Bittner 1 Dr. Discoid lupus erythematosus presenting as acneiform pitting scars. The clinical manifestations of CCLE are multiple and varied. The bullous lesions in LE do not respond to treatment with only systemic corticosteroids. We report a case of a year-old girl who presented with a vesiculobullous eruption on her face, neck, trunk and genital and oral mucosa, as well as anemia, sterile pyuria, ANA 1: J Pak Med Assoc.

With discontinuation of the tetracycline there was an acute recurrence of the lesions.